The LU Neuroscience Graduate School pre-lunch seminars, 12th of March - Lund, Sweden

Tuesday March 12 2013 between 12 noon and 1 pm at BMC A10, seminar room A1021 Graduate student Magdalena Kauczynska Karlsson will present her project entitled “Found in transcription: Accurate Parkinson’s disease classification in peripheral blood” as her mandatory pre-dissertation prior to her dissertation in Norway.

Magdalena is a graduate student at the Norwegian University of Life Sciences. Her main supervisor is Prof. Solve Sæbø, Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences and her co-supervisors are Dr. Anders Lönneborg; DiaGenic ASA and Dr. Trygve Almøy; Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Norway.

Outline:A blood-based test for the early detection of Parkinson’s disease (PD) would be an important diagnostic tool and useful for patient selection when developing novel drugs or treatments for the disease. We applied gene expression profiling to the study of peripheral blood from 75 healthy control subjects and 79 PD patients at different stages of the disease. A model predicting PD with high accuracy was achieved. Our results support previous studies that gene expression in blood may be instrumental in the search for molecular biomarkers for PD.