Gene Expression Technology

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product, mostly proteins. The molecules that carry the information from the genes to the machinery in the cells making proteins is RNA. The more active the gene is the more RNA is produced and the amount of RNA can thus be a measure of how active an individual gene is. Gene expression technology measures the amount of this RNA.

Gene Expression Technology

  • Diseases cause subtle, systemic gene responses throughout the body, including the circulatory system.
  • The unique gene expression profile can be detected by measuring the amount of RNA for selected genes in peripheral blood, identified using gene expression technologies.
  • The DiaGenic technology uses sets of genes and transforms this gene expression profile into one simple and convenient diagnostic test.

The gene expression pattern of several selected genes is specific for different diseases. DiaGenic has developed algorithms that can analyse these gene profiles for the detection of Alzheimer's disease (ADtect®) and breast cancer (BCtect®), and are currently working on developing gene profiles for Parkinson's disease (PDtect®) and Mild Cognitive Impairment (MCItect™).