Martine J Piccart is Professor of Oncology at the Université Libre de Bruxelles and Head of the Department of Medicine at the Jules Bordet Institute. In 1996, Piccart founded the Breast International Group (BIG), of which she is chair. BIG is a consortium of 47 groups based in Europe, Canada, Latin America, Asia and Australasia involved in breast cancer research. In 2004 Professor Piccart founded the TRANSBIG initiative for translational research. She has received numerous awards including the Award of the European Society of Medical Oncology in 1997 for "exceptional contribution to the advancement of medical oncology". From 2006-2009, Piccart was the President of the European Organization for Research and Treatment of Cancer (EORTC).

Professor Anne-Lise Børresen Dale is Head of the Department of Genetics at the Norwegian Radium Hospital in Oslo . Professor Børresen Dale has sat on numerous boards including the Norwegian FUGE Functional Genomics Programme, the steering Committee of the European Breast Cancer Linkage consortium. She has also been a member of the Board of Directors for the American Association for Cancer Research. In 2009 Børresen-Dale was the President of the European Association for Cancer Research (EACR). Her research interests are breast and ovarian cancer and the identification of genotypes and gene expression profiles contributing to elevated cancer risk, radiation sensitivity, tumour aggressiveness and therapy resistance.

Dr Alan Hollingsworth is Medical Director of Mercy Women's Center and Mercy Cancer Center in Oklahoma City. He was a founding Medical Director of Oklahoma's first Multidisciplinary Breast Center and and longstanding interest in breast cancer risk assessment, having published the first lay text on the subject - The Truth About Breast Cancer Risk Assessment. Today, Dr. Hollingsworth's high-risk surveillance practice - one of the largest in the US - concentrates on breast cancer risk assessment and breast cancer (BRCA) genetic testing, while using multi-modality imaging for screening.

Dr Christos Sotiriou is Assistant Professor at the Medical Oncology Unit and also Head of the Functional Genomics & Translational Research Unit at the Jules Bordet Institute in the Université Libre de Bruxelles, Belgium. His research focuses on genomics and molecular biology in breast cancer and he is also a member of the Steering and Executive committee of TRANSBIG, a "sister" network of the Breast International Group which seeks to link dedicated multinational translational research to prospective clinical trials.